Histocompatibility & Immunogenetics
A collection of brief revision notes
Histocompatibility & Immunogenetics
A collection of brief revision notes
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Immunology
Leukocyte Populations
B Cell Receptor (IgG)
T Cell Receptor
The Major Histocompatibility Complex
Non-MHC Genes
Complement
Transplantation Immune Reactions
Transplantation Induction and Immunosuppressive Drugs
Lab Techniques
HLA Typing
HLA Antibody Testing
Crossmatching
Chimerism
In Silico Assays
Immunogenetics
Disease Associations
Disease Association Mechanisms
Pharmacogenetics and Infection
Linkage Disequilibrium and Hardy Weinberger Equilibrum
Transfusion
Key Antigen Systems
Human Platelet Antigens
Human Neutrophil Antigens
Transfusion Reactions
Immunological Platelet Refractoriness
Transfusion Associated Graft versus Host Disease (TA-GvHD)
Transfusion Related Acute Lung Injury (TRALI)
Neonatal Alloimmune Thrombocytopaenia (NAIT)
Neonatal Alloimmune Neutropaenia (NAIN)
Post Transfusion Purpura (PTP)
Febrile Non Haemolytic Transfusion Reactions (FNHTR)
Heparin Induced Thrombocytopenia (HIT)
Glanzmann Thrombasthenia (GT)
Key Blood Counts
HSCT
Clinical Conditions Treated with Stem cell Transplantation
Role of the Stem Cell Multidisciplinary Teams (MDT’s)
Role of HLA Matching in Stem Cell Transplant Outcome
Role of Non-HLA Genetic Factors in Stem Cell Transplant Outcome
Non-Genetic Factors which Influence HSCT Outcome
Sources of Haematopoietic Stem Cells
Stem Cell Donor Selection Strategies
Transfusion Support in HSCT
Role of Reduced Intensity Conditioning (RIC)
Role of HLA Antibodies
HSCT in Sickle Cell Disease
HSCT After Kidney Transplant
Second HSCT
Post-Transplant Monitoring
Kidney And Pancreas
History of Clinical Solid Organ Transplantation
Causes of Kidney Failure Which May lead to Kidney Transplantation
Role of the Renal Multidisciplinary Teams (MDT’s)
Role of HLA Matching In Transplant Outcome
Role of Non-HLA Genetic Factors in Transplant Outcome
Role of HLA Antibodies in Graft Survival
Application of H&I Laboratory Techniques
Post-Transplant Complications
Complex Kidney Transplant Scenarios
Kidney Allograft Rejection
Cardiothoracic Transplantation
Listing Patients for Heart Transplantation
The Heart Allocation Scheme in the UK
The Lung Allocation Scheme in the UK
Role of HLA Matching in Cardiothoracic Transplantation
Relevance of HLA Antibodies in Cardiothoracic Transplantation
Kidney After Heart Transplant
Cardiothoracic Patient Retrospective Crossmatch Interpretation
Cardiothoracic Patient Post-Transplant Follow Up
About
Transfusion
Key Antigen Systems
Transfusion Reactions
Key Blood Counts